Friday, March 25, 2011

Mesothelioma Treatment Options for Malignant Mesothelioma






Mesothelioma treatment options for malignant mesothelioma can relieve pain and provide hope for the future. In many cases, new mesothelioma treatment options can increase mesothelioma life expectancy beyond original expectations. Even if advanced malignant mesothelioma has reached a seemingly incurable stage, participating in clinical trials gives a breath of hope to the future generations of mesothelioma cancer patients.


Treatment for malignant mesothelioma can start with surgery, although this is not always recommended in mesothelioma treatment options since older patients may have a difficult time with surgery. The objective is to remove the tumor, or at least most of it, and slow down the disease. With advanced mesothelioma, the tumor has often tragically spread throughout the body and has invaded life-giving organs, making surgery more risky than living with cancer itself. However in the early stages of malignant mesothelioma, a localized tumor is more likely to be successfully removed.


Radical surgery is a mesothelioma treatment option for advanced malignant mesothelioma that has been used in small clinical trials, but has resulted in almost half the patients (48%) living at least five years past their predetermined mesothelioma life expectancy date. “Extrapleural pneumonectomy” involves removing the internal body parts that mesothelioma cancer cells love to invade. Surgery removes the parietal pleura (pleural mesothelioma), the pericardium (pericardial mesothelioma) and the diaphragm, as well as the removal of a lung. This surgery is combined with pre and post operative chemotherapy and radiotherapy. Cancer Research UK is funding a “MARS” clinical trial (mesothelioma and radical surgery) to formally undergo pilot testing. Since the patients must be followed for five years, the results are not yet available and the success of these mesothelioma treatment options has yet to be discovered. UK medical reports do claim that US trial results have thus far demonstrated that a heavier dose of radiotherapy after the EPP surgery extends mesothelioma life expectancy.


Mesothelioma treatment options almost always include chemotherapy. Progress is seen in mesothelioma treatment when chemotherapy is combined with drug therapy. There are clinical trials for mesothelioma treatment options around the world that are seeking to find the chemotherapy and drug mix that can prolong mesothelioma life expectancy. Clinical trials are listed at many cancer organizations and research hospitals, and many seek mesothelioma patients wanting mesothelioma treatment options for advanced malignant mesothelioma. In advanced malignant mesothelioma, participating in a clinical trial can be a lifesaving mesothelioma treatment option.


Mesothelioma treatment options for advanced malignant mesothelioma can also be found in clinical trials for anti-angiogenic therapy. Anti-angiogenic mesothelioma treatment options are biological therapies that revolve around blood vessel growth. A cancer needs its own blood supply to grow. Two primary chemicals contribute to growth, VEGF and FGF-2. Mesothelioma patients with advanced malignant mesothelioma have higher levels of VEGF compared to patients suffering from other cancers. The theory the clinical trials are hoping to prove is that blocking VEFG will stop the blood vessel growth that supports the cancer growth.


Mesothelioma treatment options for malignant mesothelioma also includes clinical trials in phototherapy, immunotherapy, gene therapy and other therapies. Medical specialists are scrambling to find the mesothelioma treatment options for malignant mesothelioma that can protect and cure the projected increase in mesothelioma patients of the future. Participating in clinical trials can extend mesothelioma life expectancy and provide hope for future generations.




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